Dihydroconiferyl Ferulate Isolated from <i>Dendropanax morbiferus</i> H.Lév. Suppresses Stemness of Breast Cancer Cells via Nuclear EGFR/c-Myc Signaling

Dihydroconiferyl Ferulate Isolated from <i>Dendropanax morbiferus</i> H.Lév. Suppresses Stemness of Breast Cancer Cells via Nuclear EGFR/c-Myc Signaling

Breast cancer is the leading cause of global cancer incidence and breast cancer stem cells (BCSCs) have been identified as the target to overcome breast cancer in patients. In this study, we purified a BCSC inhibitor from <i>Dendropanax morbiferus</i> H.Lév. leaves through several open c...

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Bibliographic Details
Main Authors: Yu-Chan Ko, Ren Liu, Hu-Nan Sun, Bong-Sik Yun, Hack Sun Choi, Dong-Sun Lee
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Pharmaceuticals
Subjects:
breast cancer stem cells
dihydroconiferyl ferulate
nuclear EGFR
Stat3
c-Myc
Online Access:https://www.mdpi.com/1424-8247/15/6/664

Internet

https://www.mdpi.com/1424-8247/15/6/664

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