Edoxaban Dosing Time Affects Blood Coagulation Inhibition in Rats

Coagulation–fibrinolytic system activity shows daily rhythmicity, with hypercoagulability in the morning and hypocoagulability in the evening. Consequently, the efficacy of anticoagulants may be influenced by their dosing time. Edoxaban, a selective inhibitor of the active form of coagulation factor...

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Bibliographic Details
Main Authors: Naoto Nagata, Muneo Kawasumi, Akio Fujimura, Hitoshi Ando
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2021-04-01
Series:TH Open
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1725041