TMC function, dysfunction, and restoration in mouse vestibular organs

TMC function, dysfunction, and restoration in mouse vestibular organs

Tmc1 and Tmc2 are essential pore-forming subunits of mechanosensory transduction channels localized to the tips of stereovilli in auditory and vestibular hair cells of the inner ear. To investigate expression and function of Tmc1 and Tmc2 in vestibular organs, we used quantitative polymerase chain r...

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Bibliographic Details
Main Authors: Evan M. Ratzan, John Lee, Margot A. Madison, Hong Zhu, Wu Zhou, Gwenaëlle S. G. Géléoc, Jeffrey R. Holt
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Neurology
Subjects:
vestibular
hair cell
utricle
saccule
semicircular canal
TMC1
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2024.1356614/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2024.1356614/full

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