Pharmacology of <i>Veratrum californicum</i> Alkaloids as Hedgehog Pathway Antagonists

<i>Veratrum californicum</i> contains steroidal alkaloids that function as inhibitors of hedgehog (Hh) signaling, a pathway involved in the growth and differentiation of cells and normal tissue development. This same Hh pathway is abnormally active for cell proliferation in more than 20...

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Bibliographic Details
Main Authors: Madison L. Dirks, Owen M. McDougal
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/17/1/123