Intracellular Trafficking and Translocation of Pertussis Toxin
Pertussis toxin (PT) is a multimeric complex of six proteins. The PTS1 subunit is an ADP-ribosyltransferase that inactivates the alpha subunit of heterotrimeric G<sub>i</sub>/<sub>o</sub> proteins. The remaining PT subunits form a pentamer that positions PTS1 in and above the...
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Format: | Article |
Language: | English |
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MDPI AG
2019-07-01
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Series: | Toxins |
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Online Access: | https://www.mdpi.com/2072-6651/11/8/437 |