Rational Design of AAV-rh74, AAV3B, and AAV8 with Limited Liver Targeting

Recombinant adeno-associated viruses (rAAVs) have become one of the leading gene therapies for treating a variety of diseases. One factor contributing to rAAVs’ success is the fact that a wide variety of tissue types can be transduced by different serotypes. However, one commonality amongst most ser...

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Bibliografiske detaljer
Main Authors: Christopher Chan, Kathryn K. Harris, Sergei Zolotukhin, Geoffrey D. Keeler
Format: Article
Sprog:English
Udgivet: MDPI AG 2023-10-01
Serier:Viruses
Fag:
Online adgang:https://www.mdpi.com/1999-4915/15/11/2168