Kinetochore component function in C. elegans oocytes revealed by 4D tracking of holocentric chromosomes

Abstract During cell division, chromosome congression to the spindle center, their orientation along the spindle long axis and alignment at the metaphase plate depend on interactions between spindle microtubules and kinetochores, and are pre-requisite for chromosome bi-orientation and accurate segre...

Full description

Bibliographic Details
Main Authors: Laras Pitayu-Nugroho, Mélanie Aubry, Kimberley Laband, Hélène Geoffroy, Thadshagine Ganeswaran, Audi Primadhanty, Julie C. Canman, Julien Dumont
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39702-z