Epithelial-derived galectin-9 containing exosomes contribute to the immunomodulatory effects promoted by 2’-fucosyllactose and short-chain galacto- and long-chain fructo-oligosaccharides

Epithelial-derived galectin-9 containing exosomes contribute to the immunomodulatory effects promoted by 2’-fucosyllactose and short-chain galacto- and long-chain fructo-oligosaccharides

IntroductionEarly life exposure to non-digestible oligosaccharides (NDO) or microbial components is known to affect immune development. NDO in combination with a TLR9 agonist mimicking bacterial triggers (CpG) promoted the secretion of galectins through unknown pathways. We aimed to study the contri...

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Bibliographic Details
Main Authors: Veronica Ayechu-Muruzabal, Merel de Boer, Bart Blokhuis, Alinda J. Berends, Johan Garssen, Aletta D. Kraneveld, Belinda van’t Land, Linette E. M. Willemsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
galectins
exosome
non-digestible oligosaccharide
intestinal-epithelial cells
mucosal immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1026031/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1026031/full

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