A Dirichlet-Multinomial Bayes Classifier for Disease Diagnosis with Microbial Compositions

ABSTRACT Dysbiosis of microbial communities is associated with various human diseases, raising the possibility of using microbial compositions as biomarkers for disease diagnosis. We have developed a Bayes classifier by modeling microbial compositions with Dirichlet-multinomial distributions, which...

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Bibliographic Details
Main Authors: Xiang Gao, Huaiying Lin, Qunfeng Dong
Format: Article
Language:English
Published: American Society for Microbiology 2017-12-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mSphereDirect.00536-17