Brain co‐delivery of first‐line chemotherapy drug and epigenetic bromodomain inhibitor for multidimensional enhanced synergistic glioblastoma therapy

Brain co‐delivery of first‐line chemotherapy drug and epigenetic bromodomain inhibitor for multidimensional enhanced synergistic glioblastoma therapy

Abstract Glioblastoma (GBM) is a central nervous system tumor with poor prognosis due to the rapid development of resistance to mono chemotherapy and poor brain targeted delivery. Chemoimmunotherapy (CIT) combines chemotherapy drugs with activators of innate immunity that hold great promise for GBM...

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Bibliographic Details
Main Authors: Yanjie Liu, Wendie Wang, Dongya Zhang, Yajing Sun, Fangzhou Li, Meng Zheng, David B. Lovejoy, Yan Zou, Bingyang Shi
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:Exploration
Subjects:
biomimetic
blood–brain barrier
brain‐targeted delivery
chemoimmunotherapy
glioblastoma
Online Access:https://doi.org/10.1002/EXP.20210274

Internet

https://doi.org/10.1002/EXP.20210274

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