Competition between NBS1 and ATMIN Controls ATM Signaling Pathway Choice

Competition between NBS1 and ATMIN Controls ATM Signaling Pathway Choice

Ataxia telangiectasia mutated (ATM) protein kinase activation by DNA double-strand breaks (DSBs) requires the Mre11-Rad50-NBS1 (MRN) complex, whereas ATM interactor (ATMIN) protein is required for ATM signaling induced by changes in chromatin structure. We show here that NBS1 and ATMIN proteins comp...

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Bibliographic Details
Main Authors: Tianyi Zhang, Kay Penicud, Christopher Bruhn, Joanna I. Loizou, Nnennaya Kanu, Zhao-Qi Wang, Axel Behrens
Format: Article
Language:English
Published: Elsevier 2012-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471200383X

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http://www.sciencedirect.com/science/article/pii/S221112471200383X

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