Supporting SARS-CoV-2 Papain-Like Protease Drug Discovery: In silico Methods and Benchmarking

Supporting SARS-CoV-2 Papain-Like Protease Drug Discovery: In silico Methods and Benchmarking

The coronavirus disease 19 (COVID-19) is a rapidly growing pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Its papain-like protease (SARS-CoV-2 PLpro) is a crucial target to halt virus replication. SARS-CoV PLpro and SARS-CoV-2 PLpro share an 82.9% sequence ident...

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Bibliographic Details
Main Authors: Tamer M. Ibrahim, Muhammad I. Ismail, Matthias R. Bauer, Adnan A. Bekhit, Frank M. Boeckler
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Chemistry
Subjects:
COVID-19
docking
VS
benchmarking
DEKOIS 2.0
PLpro
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2020.592289/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2020.592289/full

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