Early onset and liver failure indicating poor prognosis of infant liver failure syndrome type 1

Early onset and liver failure indicating poor prognosis of infant liver failure syndrome type 1

Abstract Background Infantile liver failure syndrome type 1 (ILFS1, OMIM #615,438), caused by leucyl-tRNA synthase 1 (LARS1, OMIM *151,350) deficiency, is a rare autosomal-recessive disorder. The clinical manifestations, molecular-genetic features, and prognosis of LARS1 disease remain largely elusi...

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Bibliographic Details
Main Authors: Shu-Yuan Li, Jia-Yan Feng, Zhong-Die Li, Teng Liu
Format: Article
Language:English
Published: BMC 2024-06-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Acute liver failure
Genotype
Survival analysis
LARS1
Leucyl-tRNA synthase 1
Online Access:https://doi.org/10.1186/s13023-024-03229-3

Internet

https://doi.org/10.1186/s13023-024-03229-3

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