Altered entrainment to the day/night cycle attenuates the daily rise in circulating corticosterone in the mouse.

The suprachiasmatic nucleus (SCN) is a circadian oscillator entrained to the day/night cycle via input from the retina. Serotonin (5-HT) afferents to the SCN modulate retinal signals via activation of 5-HT1B receptors, decreasing responsiveness to light. Consequently, 5-HT1B receptor knockout (KO) m...

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Bibliographic Details
Main Authors: Patricia J Sollars, Michael J Weiser, Andrea E Kudwa, Jayne R Bramley, Malcolm D Ogilvie, Robert L Spencer, Robert J Handa, Gary E Pickard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4218825?pdf=render