Adropin correlates with aging-related neuropathology in humans and improves cognitive function in aging mice

Adropin correlates with aging-related neuropathology in humans and improves cognitive function in aging mice

Abstract The neural functions of adropin, a secreted peptide highly expressed in the brain, have not been investigated. In humans, adropin is highly expressed in astrocytes and peaks during critical postnatal periods of brain development. Gene enrichment analysis of transcripts correlating with adro...

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Bibliographic Details
Main Authors: Subhashis Banerjee, Sarbani Ghoshal, Clemence Girardet, Kelly M. DeMars, Changjun Yang, Michael L. Niehoff, Andrew D. Nguyen, Prerana Jayanth, Brittany A. Hoelscher, Fenglian Xu, William A. Banks, Kim M. Hansen, Jinsong Zhang, Eduardo Candelario-Jalil, Susan A. Farr, Andrew A. Butler
Format: Article
Language:English
Published: Nature Portfolio 2021-08-01
Series:npj Aging and Mechanisms of Disease
Online Access:https://doi.org/10.1038/s41514-021-00076-5

Internet

https://doi.org/10.1038/s41514-021-00076-5

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