Active secretion of a thermostable transglutaminase variant in Escherichia coli

Active secretion of a thermostable transglutaminase variant in Escherichia coli

Abstract Background Streptomyces mobaraenesis transglutaminase (smTG) is widely used to generate protein crosslinking or attachment of small molecules. However, the low thermostability is a main obstacle for smTG application. In addition, it is still hard to achieve the secretory expression of activ...

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Bibliographic Details
Main Authors: Xinglong Wang, Beichen Zhao, Jianhui Du, Yameng Xu, Xuewen Zhu, Jingwen Zhou, Shengqi Rao, Guocheng Du, Jian Chen, Song Liu
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Microbial Cell Factories
Subjects:
Streptomyces mobaraenesis
Transglutaminase
Thermostability
Active expression
Protein secretion
Escherichia coli
Online Access:https://doi.org/10.1186/s12934-022-01801-9

Internet

https://doi.org/10.1186/s12934-022-01801-9

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