Altered γ-aminobutyric acid neurotransmission in major depressive disorder: a critical review of the supporting evidence and the influence of serotonergic antidepressants

Alan L Pehrson, Connie Sanchez External Sourcing and Scientific Excellence, Lundbeck Research USA, Paramus, NJ, USA Abstract: Evidence suggesting that central nervous system γ-aminobutyric acid (GABA) concentrations are reduced in patients with major depressive disorder (MDD) has been pr...

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Bibliographic Details
Main Authors: Pehrson AL, Sanchez C
Format: Article
Language:English
Published: Dove Medical Press 2015-01-01
Series:Drug Design, Development and Therapy
Online Access:http://www.dovepress.com/altered-gamma-aminobutyric-acid-neurotransmission-in-major-depressive--peer-reviewed-article-DDDT