Propofol Ameliorates ox-LDL-Induced Endothelial Damage Through Enhancing Autophagy via PI3K/Akt/m-TOR Pathway: A Novel Therapeutic Strategy in Atherosclerosis

Propofol Ameliorates ox-LDL-Induced Endothelial Damage Through Enhancing Autophagy via PI3K/Akt/m-TOR Pathway: A Novel Therapeutic Strategy in Atherosclerosis

Objective: Atherosclerosis (AS) represents a common age-associated disease, which may be accelerated by oxidized low-density lipoprotein (ox-LDL)-induced endothelial cell injury. This study aimed to investigate the effects of Propofol on ox-LDL-induced endothelial damage and the underlying molecular...

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Bibliographic Details
Main Authors: Hongyi Zhou, Fan Jiang, Yufang Leng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
propofol
autophagy
atherosclerosis
PI3K/Akt/m-TOR
endothelial cells
oxidized low-density lipoprotein
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.695336/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.695336/full

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