Nonsense-Mediated mRNA Decay, a Finely Regulated Mechanism

Nonsense-Mediated mRNA Decay, a Finely Regulated Mechanism

Nonsense-mediated mRNA decay (NMD) is both a mechanism for rapidly eliminating mRNAs carrying a premature termination codon and a pathway that regulates many genes. This implies that NMD must be subject to regulation in order to allow, under certain physiological conditions, the expression of genes...

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Bibliographic Details
Main Author: Fabrice Lejeune
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biomedicines
Subjects:
nonsense-mediated mRNA decay
UPF proteins
regulation
gene expression
therapeutic perspectives
Online Access:https://www.mdpi.com/2227-9059/10/1/141

Internet

https://www.mdpi.com/2227-9059/10/1/141

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