Targeted treatment of refractory primitive neuroectodermal tumor arising from an immature teratoma with crizotinib leading to a sustained response

Abstract Here we present a case of metastatic PNET which arose from an immature teratoma that was refractory to standard Ewing sarcoma chemotherapy. This PNET was determined to have elevated levels of ALK protein via IHC. The patient was treated with crizotinib on a palliative basis with a sustained...

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Bibliographic Details
Main Authors: Benjamin M. Snyder, Alex H. Lion, Amy E. Helvie, Mark S. Marshall, Michael J. Ferguson
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.6779