A novel malaria vaccine candidate antigen expressed in Tetrahymena thermophila.

Development of effective malaria vaccines is hampered by the problem of producing correctly folded Plasmodium proteins for use as vaccine components. We have investigated the use of a novel ciliate expression system, Tetrahymena thermophila, as a P. falciparum vaccine antigen platform. A synthetic v...

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Bibliographic Details
Main Authors: Graeme J M Cowan, Ulrike Bockau, Janna Eleni-Muus, Ingo Aldag, Kay Samuel, Alison M Creasey, Marcus W W Hartmann, David R Cavanagh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3906136?pdf=render