The interdependent network of gene regulation and metabolism is robust where it needs to be

Although networks of interacting genes and metabolic reactions are interdependent, they have largely been treated as separate systems. Here the authors apply a statistical framework for interdependent networks to E. coli, and show that it is sensitive to gene and protein perturbations but robust aga...

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Bibliographic Details
Main Authors: David F. Klosik, Anne Grimbs, Stefan Bornholdt, Marc-Thorsten Hütt
Format: Article
Language:English
Published: Nature Portfolio 2017-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00587-4