Arthrogenicity of type II collagen monoclonal antibodies associated with complement activation and antigen affinity

<p>Abstract</p> <p>Background</p> <p>The collagen antibody-induced arthritis (CAIA) model, which employs a cocktail of monoclonal antibodies (mAbs) to type II collagen (CII), has been widely used for studying the pathogenesis of autoimmune arthritis. In this model, not...

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Bibliographic Details
Main Authors: Mizutani Nobuaki, Hutamekalin Pilaiwanwadee, Kadotani Tatsuya, Koobkokkruad Thongchai, Yoshino Shin
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Journal of Inflammation
Online Access:http://www.journal-inflammation.com/content/8/1/31