RAP1/TERF2IP—A Multifunctional Player in Cancer Development

Mammalian RAP1 (TERF2IP), the most conserved shelterin component, plays a pleiotropic role in the regulation of a variety of cellular processes, including cell metabolism, DNA damage response, and NF-κB signaling, beyond its canonical telomeric role. Moreover, it has been demonstrated to be involved...

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Bibliographic Details
Main Authors: Anna Deregowska, Maciej Wnuk
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/23/5970