An Efficient Catalytic DNA that Cleaves L-RNA.

Many DNAzymes have been isolated from synthetic DNA pools to cleave natural RNA (D-RNA) substrates and some have been utilized for the design of aptazyme biosensors for bioanalytical applications. Even though these biosensors perform well in simple sample matrices, they do not function effectively i...

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Bibliographic Details
Main Authors: Kha Tram, Jiaji Xia, Rachel Gysbers, Yingfu Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4422682?pdf=render