Aptamer-based nanotrains and nanoflowers as quinine delivery systems

Aptamer-based nanotrains and nanoflowers as quinine delivery systems

In this study, we designed aptamer-based self-assemblies for the delivery of quinine. Two different architectures were designed by hybridizing quinine binding aptamers and aptamers targeting Plasmodium falciparum lactate dehydrogenase (PfLDH): nanotrains and nanoflowers. Nanotrains consisted in cont...

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Bibliographic Details
Main Authors: Mengyuan Cao, Anthony Vial, Laetitia Minder, Aurore Guédin, Sébastien Fribourg, Laurent Azéma, Cécile Feuillie, Michael Molinari, Carmelo Di Primo, Philippe Barthélémy, Leblond Chain Jeanne
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:International Journal of Pharmaceutics: X
Subjects:
Nanotrain
Nanoflower
Targeted delivery
DNA aptamer
Quinine
Malaria
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156723000166

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http://www.sciencedirect.com/science/article/pii/S2590156723000166

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