Regulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane Targeting
Phosphatidylinositol 3-kinase-related kinases (PIKKs) play vital roles in the regulation of cell growth, proliferation, survival, and consequently metabolism, as well as in the cellular response to stresses such as ionizing radiation or redox changes. In humans six family members are known to date,...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-09-01
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Series: | Membranes |
Subjects: | |
Online Access: | http://www.mdpi.com/2077-0375/5/4/553 |