Regulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane Targeting

Regulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane Targeting

Phosphatidylinositol 3-kinase-related kinases (PIKKs) play vital roles in the regulation of cell growth, proliferation, survival, and consequently metabolism, as well as in the cellular response to stresses such as ionizing radiation or redox changes. In humans six family members are known to date,...

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Bibliographic Details
Main Authors:	Maristella De Cicco, Munirah S. Abd Rahim, Sonja A. Dames
Format:	Article
Language:	English
Published:	MDPI AG 2015-09-01
Series:	Membranes
Subjects:	phosphatidylinositol-3 kinase-related kinase membrane targeting protein–membrane interaction signal transduction mTOR ATM ATR DNA-PKcs SMG-1 TRRAP
Online Access:	http://www.mdpi.com/2077-0375/5/4/553

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