Construction of a risk scoring system using clinical factors and RYR2 polymorphisms for bleeding complications in patients on direct oral anticoagulants

Construction of a risk scoring system using clinical factors and RYR2 polymorphisms for bleeding complications in patients on direct oral anticoagulants

Introduction: Bleeding is one of the most undesirable complications of direct oral anticoagulants (DOACs). While the ryanodine receptor (RYR2) has been related to cardiac diseases, research on bleeding complications is lacking. This study aimed to elucidate the association between RYR2 and bleeding...

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Bibliographic Details
Main Authors: Eun Jeong Jang, Jung Sun Kim, Seo A. Choi, Jeong Yee, Tae-Jin Song, Junbeom Park, Hye Sun Gwak
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Pharmacology
Subjects:
direct oral anticoagulants
bleeding
ryanodine receptors
pharmacogenomics
gene polymorphism
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1290785/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1290785/full

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