Genetic variants of ABCC8 and clinical manifestations in eight Chinese children with hyperinsulinemic hypoglycemia

Genetic variants of ABCC8 and clinical manifestations in eight Chinese children with hyperinsulinemic hypoglycemia

Abstract Background ABCC8 variants can cause hyperinsulinemia by activating or deactivating gene expression. This study used targeted exon sequencing to investigate genetic variants of ABCC8 and the associated phenotypic features in Chinese patients with hyperinsulinemic hypoglycemia (HH). Methods W...

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Bibliographic Details
Main Authors: Guoying Chang, Lingwen Ying, Qianwen Zhang, Biyun Feng, Ruen Yao, Yu Ding, Juan Li, Xiaodong Huang, Yongnian Shen, Tingting Yu, Jian Wang, Xiumin Wang
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Endocrine Disorders
Subjects:
Hyperinsulinemic hypoglycemia
ABCC8
Clinical presentation
Gene abnormalities
Therapy
Online Access:https://doi.org/10.1186/s12902-023-01527-8

Internet

https://doi.org/10.1186/s12902-023-01527-8

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