Genitourinary manifestations of Lynch syndrome in the urological practice

Genitourinary manifestations of Lynch syndrome in the urological practice

Objective: Lynch syndrome (LS) is an autosomal dominant hereditary disorder resulting from germline mutation in at least one of the four mismatch repair genes or in EPCAM gene. From a clinical perspective, LS patients exhibit an increased predisposition to multiple primary malignancies and early age...

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Bibliographic Details
Main Authors: Chiara Lonati, Claudio Simeone, Nazareno Suardi, Philippe E. Spiess, Andrea Necchi, Marco Moschini
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Asian Journal of Urology
Subjects:
Hereditary disease
Hereditary nonpolyposis colorectal cancer
Lynch syndrome
Mismatch repair
Upper tract urothelial carcinoma
Online Access:http://www.sciencedirect.com/science/article/pii/S2214388222000959

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http://www.sciencedirect.com/science/article/pii/S2214388222000959

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