The m6A-methylated mRNA pattern and the activation of the Wnt signaling pathway under the hyper-m6A-modifying condition in the keloid

The m6A-methylated mRNA pattern and the activation of the Wnt signaling pathway under the hyper-m6A-modifying condition in the keloid

Purpose: The present study was carried out to investigate the global m6A-modified RNA pattern and possible mechanisms underlying the pathogenesis of keloid.Method: In total, 14 normal skin and 14 keloid tissue samples were first collected on clinics. Then, three samples from each group were randomly...

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Bibliographic Details
Main Authors: Can-Xiang Lin, Zhi-Jing Chen, Qi-Lin Peng, Ke-Rong Xiang, Du-Qing Xiao, Ruo-Xi Chen, Taixing Cui, Yue-Sheng Huang, Hong-Wei Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
keloid
m6A modification
fibroblasts
the Wnt signaling pathway
RNA sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.947337/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.947337/full

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