Mitochondrial targeted coenzyme Q, superoxide, and fuel selectivity in endothelial cells.

Previously, we reported that the "antioxidant" compound "mitoQ" (mitochondrial-targeted ubiquinol/ubiquinone) actually increased superoxide production by bovine aortic endothelial (BAE) cell mitochondria incubated with complex I but not complex II substrates.To further define the...

Full description

Bibliographic Details
Main Authors: Brian D Fink, Yunxia O'Malley, Brian L Dake, Nicolette C Ross, Thomas E Prisinzano, William I Sivitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2621344?pdf=render