Domino Aldol-S<sub>N</sub>Ar-Dehydration Sequence for [3+3] Annulations to Prepare Quinolin-2(1<i>H</i>)-ones and 1,8-Naphthyridin-2(1<i>H</i>)-ones
A domino aldol-S<sub>N</sub>Ar-dehydration [3+3] annulation strategy has been utilized to fuse six-membered cyclic amides onto aromatic substrates. 2-Arylacetamides have been reacted with 2-fluorobenzaldehyde derivatives activated toward S<sub>N</sub>Ar reaction by an electro...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-08-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/28/15/5856 |