Targeting of the Peritumoral Adipose Tissue Microenvironment as an Innovative Antitumor Therapeutic Strategy

Targeting of the Peritumoral Adipose Tissue Microenvironment as an Innovative Antitumor Therapeutic Strategy

The tumor microenvironment (TME) plays a key role in promoting and sustaining cancer growth. Adipose tissue (AT), due to its anatomical distribution, is a prevalent component of TME, and contributes to cancer development and progression. Cancer-associated adipocytes (CAAs), reprogrammed by cancer st...

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Bibliographic Details
Main Authors: Melania Lo Iacono, Chiara Modica, Gaetana Porcelli, Ornella Roberta Brancato, Giampaolo Muratore, Paola Bianca, Miriam Gaggianesi, Alice Turdo, Veronica Veschi, Matilde Todaro, Simone Di Franco, Giorgio Stassi
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomolecules
Subjects:
tumor microenvironment
adipose tissue
cancer stem cells
adipokines
exosomes
target therapy
Online Access:https://www.mdpi.com/2218-273X/12/5/702

Internet

https://www.mdpi.com/2218-273X/12/5/702

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