Unique plasma metabolite signature for adolescents with Klinefelter syndrome reveals altered fatty acid metabolism

Unique plasma metabolite signature for adolescents with Klinefelter syndrome reveals altered fatty acid metabolism

Conditions related to cardiometabolic disease, including metabolic syndrome and type 2 diabetes, are common among men with Klinefelter syndrome (KS). The molecular mechanisms underlying this aberrant metabolism in KS are largely unknown, although there is an assumption that chronic testosterone defi...

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Bibliographic Details
Main Authors: Shanlee M Davis, Rhianna Urban, Angelo D’Alessandro, Julie A Reisz, Christine L Chan, Megan Kelsey, Susan Howell, Nicole Tartaglia, Philip Zeitler, Peter Baker II
Format: Article
Language:English
Published: Bioscientifica 2023-04-01
Series:Endocrine Connections
Subjects:
metabolomics
klinefelter syndrome
sex chromosome aneuploidy
fatty acid metabolism
mitochondrial function
Online Access:https://ec.bioscientifica.com/view/journals/ec/12/5/EC-22-0523.xml

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https://ec.bioscientifica.com/view/journals/ec/12/5/EC-22-0523.xml

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