Sophocarpine alleviates doxorubicin-induced heart injury by suppressing oxidative stress and apoptosis

Abstract Doxorubicin (DOX) is an effective anti-tumor drug accompanied with many side effects, especially heart injury. To explore what effects of sophocarpine (SOP) on DOX-induced heart injury, this study conducted in vivo experiment and in vitro experiment, and the C57BL/6J mice and the H9C2 cells...

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Bibliographic Details
Main Authors: Hong-jin Zhang, Yang Fu, Huang Zhang, Ze-qun Lai, Yi-Fei Dong
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-51083-3