Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans

Abstract The JmjC family of 2-oxoglutarate dependent oxygenases catalyse a range of hydroxylation and demethylation reactions in humans and other animals. Jumonji domain-containing 7 (JMJD7) is a JmjC (3S)-lysyl-hydroxylase that catalyses the modification of Developmentally Regulated GTP Binding Pro...

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Bibliographic Details
Main Authors: Rasheduzzaman Chowdhury, Martine I. Abboud, James Wiley, Anthony Tumber, Suzana Markolovic, Christopher J. Schofield
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-10028-y