Exploring complexity of class-A Beta-lactamase family using physiochemical-based multiplex networks

Abstract The Beta-lactamase protein family is vital in countering Beta-lactam antibiotics, a widely used antimicrobial. To enhance our understanding of this family, we adopted a novel approach employing a multiplex network representation of its multiple sequence alignment. Each network layer, derive...

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Bibliographic Details
Main Authors: Pradeep Bhadola, Nivedita Deo
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48128-y