Dysfunction of CCR1+ decidual macrophages is a potential risk factor in the occurrence of unexplained recurrent pregnancy loss

Dysfunction of CCR1+ decidual macrophages is a potential risk factor in the occurrence of unexplained recurrent pregnancy loss

Recurrent pregnancy loss (RPL) puzzles 1–3% of women of childbearing age worldwide. Immunological factors account for more than 60% of cases of unexplained RPL (URPL); however, the underlying mechanism remains unclear. Here, using single-cell sequencing data and functional experiments with clinical...

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Bibliographic Details
Main Authors: Yifei Sang, Yanhong Li, Ling Xu, Jiajia Chen, Dajin Li, Meirong Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
decidual macrophages
CCR1
CCL8
trophoblasts
epithelial-to-mesenchymal transition
unexplained recurrent pregnancy loss
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1045532/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1045532/full

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