Caught between Two Genes: Accounting for Operonic Gene Structure Improves Prokaryotic RNA Sequencing Quantification
ABSTRACT RNA sequencing (RNA-seq) has matured into a reliable and low-cost assay for transcriptome profiling and has been deployed across a range of systems. The computational tool space for the analysis of RNA-seq data has kept pace with advances in sequencing. Yet tool development has largely cent...
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Format: | Article |
Language: | English |
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American Society for Microbiology
2021-02-01
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Series: | mSystems |
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Online Access: | https://journals.asm.org/doi/10.1128/mSystems.01256-20 |