Caught between Two Genes: Accounting for Operonic Gene Structure Improves Prokaryotic RNA Sequencing Quantification

ABSTRACT RNA sequencing (RNA-seq) has matured into a reliable and low-cost assay for transcriptome profiling and has been deployed across a range of systems. The computational tool space for the analysis of RNA-seq data has kept pace with advances in sequencing. Yet tool development has largely cent...

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Bibliographic Details
Main Author: Taylor Reiter
Format: Article
Language:English
Published: American Society for Microbiology 2021-02-01
Series:mSystems
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mSystems.01256-20