Antibody Aggregation: Insights from Sequence and Structure

Monoclonal antibodies (mAbs) are the fastest-growing biological therapeutics with important applications ranging from cancers, autoimmunity diseases and metabolic disorders to emerging infectious diseases. Aggregation of mAbs continues to be a major problem in their developability. Antibody aggregat...

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Bibliographic Details
Main Authors: Wei Li, Ponraj Prabakaran, Weizao Chen, Zhongyu Zhu, Yang Feng, Dimiter S. Dimitrov
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Antibodies
Subjects:
Online Access:http://www.mdpi.com/2073-4468/5/3/19