Antibody Aggregation: Insights from Sequence and Structure

Antibody Aggregation: Insights from Sequence and Structure

Monoclonal antibodies (mAbs) are the fastest-growing biological therapeutics with important applications ranging from cancers, autoimmunity diseases and metabolic disorders to emerging infectious diseases. Aggregation of mAbs continues to be a major problem in their developability. Antibody aggregat...

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Bibliographic Details
Main Authors:	Wei Li, Ponraj Prabakaran, Weizao Chen, Zhongyu Zhu, Yang Feng, Dimiter S. Dimitrov
Format:	Article
Language:	English
Published:	MDPI AG 2016-09-01
Series:	Antibodies
Subjects:	monoclonal antibodies antibody aggregation protein unfolding antibody domains antibody drug conjugates
Online Access:	http://www.mdpi.com/2073-4468/5/3/19

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