Ultrasound assisted Mizoroki–Heck reaction catalyzed by Pd/C: Synthesis of 3-vinyl indoles as potential cytotoxic agents
The Pd/C–PPh3 catalyst system facilitated the C–C bond forming reaction between 3-iodo-1-methyl-1H-indole and various terminal alkenes under ultrasound irradiation. The present ultrasound assisted Mizoroki–Heck coupling afforded a number of 3-vinyl indole derivatives in good to acceptable yields. Tw...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-12-01
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Series: | Arabian Journal of Chemistry |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535216000277 |