Quality control and in vitro antioxidant potential of Coriandrum sativum Linn.
Background: Coriandrum sativum Linn., commonly known as coriander, is a well-known spice and drug in India. It has various health-related benefits and used in various Unani formulations. In this present study, quality assessment of coriander fruits was carried out by studying anatomical characters,...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
| Subjects: | |
| Online Access: | http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2015;volume=7;issue=4;spage=280;epage=283;aulast=Singh |
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| author | Mhaveer Singh E T Tamboli Y T Kamal Wasim Ahmad S H Ansari Sayeed Ahmad |
| author_facet | Mhaveer Singh E T Tamboli Y T Kamal Wasim Ahmad S H Ansari Sayeed Ahmad |
| author_sort | Mhaveer Singh |
| collection | DOAJ |
| description | Background: Coriandrum sativum Linn., commonly known as coriander, is a well-known spice and drug in India. It has various health-related benefits and used in various Unani formulations. In this present study, quality assessment of coriander fruits was carried out by studying anatomical characters, physicochemical tests, and chemoprofiling using high performance thin layer chromatography (HPTLC) and gas chromatography-mass spectroscopy (GC-MS) along with in vitro antioxidant potential. Materials and Methods: Standardization was carried out as per the pharmacopeial guidelines. Estimation of heavy metals, pesticides, and aflatoxins was carried out to ascertain the presence of any contaminant in the sample. Chemoprofiling was achieved by thin layer chromatography (TLC) by optimizing the mobile phase for different extracts. The most of the pharmacological activities of coriander are based on volatile oil constituents. Hence, GC-MS profiling was also carried out using hexane-soluble fraction of hydro-alcoholic extract. The total phenolic contents and in vitro antioxidant efficacy were determined using previously established methods. Results: The quality control and anatomical studies were very valuable for the identification whereas good antioxidant potential was observed when compared to ascorbic acid. The drug was found free of contaminant when analyzed for pesticides and aflatoxins whereas heavy metals were found under reported limits. Conclusion: The work embodied in this present research can be utilized for the identification and the quality control of the coriander fruit. |
| first_indexed | 2024-04-13T07:12:35Z |
| format | Article |
| id | doaj.art-7726b7fdc1604a0aa450e17d32359b1e |
| institution | Directory Open Access Journal |
| issn | 0975-7406 0976-4879 |
| language | English |
| last_indexed | 2024-04-13T07:12:35Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj.art-7726b7fdc1604a0aa450e17d32359b1e2022-12-22T02:56:51ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0975-74060976-48792015-01-017428028310.4103/0975-7406.168026Quality control and in vitro antioxidant potential of Coriandrum sativum Linn.Mhaveer SinghE T TamboliY T KamalWasim AhmadS H AnsariSayeed AhmadBackground: Coriandrum sativum Linn., commonly known as coriander, is a well-known spice and drug in India. It has various health-related benefits and used in various Unani formulations. In this present study, quality assessment of coriander fruits was carried out by studying anatomical characters, physicochemical tests, and chemoprofiling using high performance thin layer chromatography (HPTLC) and gas chromatography-mass spectroscopy (GC-MS) along with in vitro antioxidant potential. Materials and Methods: Standardization was carried out as per the pharmacopeial guidelines. Estimation of heavy metals, pesticides, and aflatoxins was carried out to ascertain the presence of any contaminant in the sample. Chemoprofiling was achieved by thin layer chromatography (TLC) by optimizing the mobile phase for different extracts. The most of the pharmacological activities of coriander are based on volatile oil constituents. Hence, GC-MS profiling was also carried out using hexane-soluble fraction of hydro-alcoholic extract. The total phenolic contents and in vitro antioxidant efficacy were determined using previously established methods. Results: The quality control and anatomical studies were very valuable for the identification whereas good antioxidant potential was observed when compared to ascorbic acid. The drug was found free of contaminant when analyzed for pesticides and aflatoxins whereas heavy metals were found under reported limits. Conclusion: The work embodied in this present research can be utilized for the identification and the quality control of the coriander fruit.http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2015;volume=7;issue=4;spage=280;epage=283;aulast=SinghAntioxidantCoriandrum sativum Linn.physicochemicalquality controlthin layer chromatography fingerprint |
| spellingShingle | Mhaveer Singh E T Tamboli Y T Kamal Wasim Ahmad S H Ansari Sayeed Ahmad Quality control and in vitro antioxidant potential of Coriandrum sativum Linn. Journal of Pharmacy and Bioallied Sciences Antioxidant Coriandrum sativum Linn. physicochemical quality control thin layer chromatography fingerprint |
| title | Quality control and in vitro antioxidant potential of Coriandrum sativum Linn. |
| title_full | Quality control and in vitro antioxidant potential of Coriandrum sativum Linn. |
| title_fullStr | Quality control and in vitro antioxidant potential of Coriandrum sativum Linn. |
| title_full_unstemmed | Quality control and in vitro antioxidant potential of Coriandrum sativum Linn. |
| title_short | Quality control and in vitro antioxidant potential of Coriandrum sativum Linn. |
| title_sort | quality control and in vitro antioxidant potential of coriandrum sativum linn |
| topic | Antioxidant Coriandrum sativum Linn. physicochemical quality control thin layer chromatography fingerprint |
| url | http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2015;volume=7;issue=4;spage=280;epage=283;aulast=Singh |
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