Perineural injections of incobotulinumtoxin-A for diabetic neuropathic pain of the lower extremities: protocol for a phase II, single-centre, double-blind, randomised, placebo-controlled trial (the PINBOT study)
Introduction Diabetic neuropathic pain (DNP) is a debilitating complication affecting 15–20% of people with diabetes and is a predictor of depression, poor sleep and decreased quality of life. Current pharmacological treatments are often insufficient and have significant side-effects. Subcutaneous o...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2024-01-01
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Series: | BMJ Open |
Online Access: | https://bmjopen.bmj.com/content/14/1/e074372.full |