Beyond the Anticodon: tRNA Core Modifications and Their Impact on Structure, Translation and Stress Adaptation

Transfer RNAs (tRNAs) are heavily decorated with post-transcriptional chemical modifications. Approximately 100 different modifications have been identified in tRNAs, and each tRNA typically contains 5–15 modifications that are incorporated at specific sites along the tRNA sequence. These modificati...

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Bibliographic Details
Main Authors: Marcel-Joseph Yared, Agathe Marcelot, Pierre Barraud
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/15/3/374