Redox modulation of FAK controls melanoma survival--role of NOX4.

Studies have demonstrated that reactive oxygen species (ROS) generated by NADPH oxidase are essential for melanoma proliferation and survival. However, the mechanisms by which NADPH oxidase regulates these effects are still unclear. In this work, we investigate the role of NADPH oxidase-derived ROS...

Full description

Bibliographic Details
Main Authors: Cristiane Ribeiro-Pereira, João Alfredo Moraes, Mariele de Jesus Souza, Francisco R Laurindo, Maria Augusta Arruda, Christina Barja-Fidalgo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4050056?pdf=render