Improving effector functions of antibodies for cancer treatment: Enhancing ADCC and CDC

Akito Natsume, Rinpei Niwa, Mitsuo SatohAntibody Research Laboratories, Research Division, Kyowa Hakko Kirin Co., Ltd.,/Machida-shi, Tokyo, JapanAbstract: As platforms for therapeutic agents, monoclonal antibodies (MAbs) have already been approved, and several MAbs have demonstrated clinical effecti...

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Bibliographic Details
Main Authors: Akito Natsume, Rinpei Niwa, Mitsuo Satoh
Format: Article
Language:English
Published: Dove Medical Press 2008-12-01
Series:Drug Design, Development and Therapy
Online Access:http://www.dovepress.com/improving-effector-functions-of-antibodies-for-cancer-treatment-enhanc-a2721