Stepwise-targeting and hypoxia-responsive liposome AMVY@NPs carrying siYAP and verteporfin for glioblastoma therapy

Stepwise-targeting and hypoxia-responsive liposome AMVY@NPs carrying siYAP and verteporfin for glioblastoma therapy

Abstract Background The Hippo pathway is a conserved tumour suppressor signalling pathway, and its dysregulation is often associated with abnormal cell growth and tumorigenesis. We previously revealed that the transcriptional coactivator Yes-associated protein (YAP), the key effector of the Hippo pa...

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Bibliographic Details
Main Authors: Ji Qi, Long Zhang, Zhongyu Ren, Yi Yuan, Jiahao Yu, Yining Zhang, Linbo Gu, Xu Wang, Yan Wang, Haoyue Xu, Rutong Yu, Xiuping Zhou
Format: Article
Language:English
Published: BMC 2024-08-01
Series:Journal of Nanobiotechnology
Subjects:
Glioblastoma
siYAP
VP
Nanomedicine
Polymetronidazole
Online Access:https://doi.org/10.1186/s12951-024-02776-y

Internet

https://doi.org/10.1186/s12951-024-02776-y

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